Bio/AI Software EngineerBio/AI Software Engineer

BioAI Software Engineer vs the World - How This Role Differs from Bioinformaticians, ML Engineers, and More

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Jan Piotrzkowski
Jan Piotrzkowski

After I invented the title BioAI Software Engineer, one question kept popping up:

“How is that different from a bioinformatician or ML engineer?”

It’s a fair question - because at first glance, it does sound like it overlaps with other roles.

But it’s not the same.

Let’s break down how this role is different from its closest neighbors in the tech-bio space.


Bioinformatician vs. BioAI Software Engineer

Bioinformaticians usually work in academia or research settings. Their main focus is writing scripts or using tools to process and analyze biological data-think genome sequences, protein alignments, and statistical outputs.

BioAI Software Engineers, on the other hand, build production-grade tools and systems that use machine learning to interact with biological data.

Bioinformatician BioAI Software Engineer
Primarily R/Python scripting Python, Rust, backend frameworks
Often builds one-off pipelines Builds scalable software systems
Deep in genomics, proteomics Works across molecular biology & AI
Research-focused Product-focused

ML Engineer vs. BioAI Software Engineer

Machine Learning Engineers are excellent at designing and optimizing models. They focus on performance, scaling, deployment, and infrastructure.

But most ML Engineers know little biology. They’re solving problems in finance, NLP, computer vision, or recommendation systems.

BioAI Software Engineers operate in a domain where biology is the input, and ML is the tool - not the product.

ML Engineer BioAI Software Engineer
Strong on ML theory Strong on applying ML to biology
Works on NLP, vision, etc. Works on proteins, genes, cells
Rarely understands biological systems Understands molecular structures and processes
MLOps focus Molecular simulation & bio-pipelines focus

Computational Biologist vs. BioAI Software Engineer

This one’s close.

Computational Biologists do a lot of the work BioAI SEs do—modeling molecules, simulations, data analysis—but typically in research labs and academic institutions.

They write code, but the focus is research-first.

A BioAI Software Engineer is a developer-first, builder-first. They may publish, but their DNA (pun intended) is in product and infrastructure, not papers.

Computational Biologist BioAI Software Engineer
Academic / research setting Industry / product setting
Publishes papers Builds apps, tools, platforms
Biology-first, coding second Coding-first, biology second
Often uses MATLAB, R Python, Rust, TypeScript

AI Researcher vs. BioAI Software Engineer

AI Researchers build new models and push theoretical boundaries. They’re behind innovations like GPT, AlphaFold, or diffusion models.

But they don’t usually apply these directly to real-world systems.

BioAI Software Engineers integrate, apply, and productionize these breakthroughs for specific biological domains.

AI Researcher BioAI Software Engineer
Focus: theory, algorithms Focus: applied tools, systems
Builds models from scratch Integrates existing models
Publishes papers Ships products
Limited domain context Deep domain alignment (bio)

So where does BioAI Software Engineer fit?

Right in the middle.

It's the glue between biology and machine learning. Between research and production. Between wet labs and software engineering.

It’s not a replacement for the roles above. It’s a bridge between them.


Why this matters

If you're a developer who:

  • Loves AI
  • Is curious about biology
  • Wants to build tools, not just run notebooks
  • Dreams of solving real-world problems in health, genetics, or biotech...

...then maybe you’ve been looking for this role, too.

Now you have a name for it.